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KCUMB's Science Friday Talks features lectures and presentations from a broad spectrum of national and international speakers on topics that are relevant to the diverse University community.
Presentations are from noon to 1 p.m. on KCUMB campus, unless otherwise noted. Lectures are open to KCUMB students, faculty, staff and alumni.
For questions about this event, please contact Dana Buchanan at email@example.com.
Steven Gustafson, D.O., Assistant Professor of Pathology, KCUMB | Read biography
A physician or research scientist with a desire to work in a limited resource environment faces many challenges. Consideration must be given to economic and cultural values, cultural differences and norms specific to a particular population. These are important factors to consider when planning and conducting research and or practicing medicine. Support for activities we often take for granted, like running water, electricity, infectious diseases, and good transportation to name a few, can become significant barriers to success. Join Dr. Gustafson as he shares his personal experiences, successes and challenges.
Flavia Costa, Ph.D., Research Instructor, College of Biosciences, KCUMB | Read biography
Sickle Cell Disease (SCD) is a common genetic disorder that affects approximately 1 in 1,800 newborns in the U.S. including 1 in 400 African-American infants. High levels of fetal hemoglobin (HbF - g-globin gene) in adulthood is the most potent modifier of disease severity. Thus, research has focused on elucidating pathways to increase g-globin expression in adulthood, as therapy for SCD. While SCD treatment strategies are focusing in the modulation of the globin genes (g-globin gene expression), other therapies need to be implemented early in the infant’s life to manage the severity of SCD clinical symptoms.
Therefore, this presentation will focus on two different biological pathways that might lead into the development of new SCD therapeutic strategies. The first strategy focuses on the activation/ alleviation of repression of fetal hemoglobin by modulating transcriptional factories. The second strategy is focused on management SCD clinical symptoms such vaso-occlusive crisis by manipulating the early definitive erythropoiesis with zinc treatment and inhibition of oxidative stress cascade.
Francesco Cerritelli, D.O., Professor of Cranial and
Sacrum Techniques, ICOM, International College of Osteopathic Medicine,
Milan, Italy | View C.V. (PDF)
Research in osteopathy has been steadily rising during the last decade making quality of studies and results constantly more reliable. Different medical fields and age groups were selected to scientifically prove the clinical validity of osteopathic procedures. Upon that, few medical conditions have been demonstrated to clearly benefit of osteopathic treatment. Many others started to shed light on the possible role of osteopathy. The aim of this lecture is to provide a review of osteopathic research literature, critically evaluating studies published in all age groups and medical fields. Another objective is to create the basis to open profitable discussion and plan future projects considering the role of osteopathy in public health.
OMM and Anatomy Fellows
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