Science Friday Talks

KCU-Kansas City

Get up-to-the-minute research discoveries on hot topics, such as Alzheimer’s disease, biological warfare and cancer.

Science Friday Talks

KCU-Kansas City

Get up-to-the-minute research discoveries on hot topics, such as Alzheimer’s disease, biological warfare and cancer.

Prions Propagate Innate Immune Signaling

Dr. Randal Halfman
Assistant Investigator, Stowers Institute for Medical Research

Friday, May 5, 2017
Noon-1 p.m.
Student Activity Center, Rooms 204-206, KCU Campus
1750 Independence Avenue
Kansas City, Mo.

Talk Summary: Dr. Halfmann will discuss recent developments in the field of prions (protein-based genetic elements), including recent work from his lab iden-tifying essential roles for functional prions in human inflammatory signaling.

               

Bio: After obtaining my PhD in Biology with Susan Lindquist at MIT, I transitioned directly to an independent research career at UT Southwestern Medical Center. As an independent postdoctoral fellow there, I secured NIH funding to build a research program that uses yeast genetics, molecular biology, and biochemistry to explore the contributions of protein aggre-gation to gene regulation and phenotypic heterogeneity. I discovered that self-propagating protein aggregates known as prions function to enforce cell fate commitment in organisms ranging from budding yeast to humans.

In 2015 I became an Assistant Investigator at the Stowers Institute in Kansas City, MO, where my lab now studies how nucleation-limited pro-tein phase transitions afford kinetic control of cell signaling and developmental processes, as well as contribute to age-associated diseases.


Please contact Gwen Dodd in the Office of Research and Sponsored Programs at gdodd@kcumb.edu with questions.