• Alexandre Shnyra, MD, PhD

    Associate Professor
    • Department: Basic Sciences

    Curriculum Vitae


    • Ph.D. in Biochemistry, All-Union Cardiology Research Center, Academy of Medical Sciences of the USSR, Moscow, USSR, 1985
    • M.D., Pirogov Medical Institute. Moscow, USSR, 1979
    • B.S. in Biophysics, Pirogov Medical Institute. Moscow, USSR, 1979

    Teaching Interests/Courses

    • Clinical and Molecular Immunology
    • Biochemistry
    • Microbiology
    • Cell Biology
    • Molecular Biology

    Research Interests

    • PGE2 in Regulation of Immuno-Inflammatory Responses
    • EP2/EP4 PGE2 Receptors in Regulation of Macrophages
    • Immuno-Editing in Tumor Microenvironment
    • Tumor-Associated Macrophages
    • MicroRNA-Controlled Reprogramming of Tumor-Associated Macrophages


    • Clonning of NR2B Subunit of N-Methyl-D-Aspartate Receptor, NY GenTech, 01/2001 - 12/2005
      NMDA receptors function in synaptic plasticity, neuronal development and excitotoxicity. NR2B subunit-containing NMDA receptors place a key role in learning and chronic pain.
    • LPS-Directed Macrophage Innate Responses to Infections, NIH, 04/2000 - 03/2005
      The central hypothesis of my research is that macrophages respond to environmental signals by the production of immunoregulatory cytokines and other inflammatory mediators that selectively reprogram these cells for a predominant phenotypic response.


    • Research Fellowship in Immunology, Human Frontier Science Program, Strasbourg, France, 01/1993
    • The Young Research Award, The International Society for Artificial Organs (Japan), 10/1989
    • The Silver Medal of the Exhibition of National Achievements of the USSR, Russian Academy of Sciences, 11/1988

    Professional Affiliations

    • Member, 02/2000 - Present, American Association of Immunologists

      The AAI is an association of scientists dedicated to advancing the knowledge of immunology and its related disciplines, fostering the interchange of ideas and information among investigators.
    • Member, 03/1999 - Present, Society for Leukocyte Biology

      The goal of the Society is promoting and extending current understanding of the importance of leukocyte biology, particularly in regard to the physiology of these cells and their relationship to the immune system.
    • Member, 10/1996 - Present, International Endotoxin and Innate Immunity Society

      The primary goal of the IEIIS is to promote scientific knowledge on all aspects of endotoxin research.

    Community Service

    • Endurance training of KCUMB students, 10/01/2011 - Present, KCUMB

      To meet the demands of a new generation of KCUMB students who want to become endurance athletes and come from all backgrounds and ability levels.

    Outside Interests

    • Ultramarathon Cycling
    • Ironman Triathlon
    • Marathons

    Last updated on: 10/3/2012 4:23:00 PM