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The Institutional Animal Care and Use Committee reviews all protocols involving research with live vertebrate animals. The committee ensures such protocols adequately protect the health and welfare of animals utilized for research.
The Public Health Services and USDA provide the bulk of regulations governing protections for animal research, to which the IACUC ensures protocols comply. Before any research with animals is initiated at the University, investigators must apply and receive approval from the IACUC.
Please plan on at least a month between the time an application is submitted and the time a decision is rendered.
Various factors pertaining to a study can lead to decisions taking more than a month, so please consider this in your study planning. Forms to submit to the IACUC are available on IRBNet.
Before any research can be initiated, all required training must be completed. Use the resources found in the Compliance Training section to determine what training is needed.
When do I need to complete an application?Complete the necessary applications if your research involves:
Does secondary analysis of existing data need IRB approval?Yes, research involving secondary analysis of existing data must have IRB review to ensure the original data was collected properly and ethically, and that objectives of secondary analysis keep with those for which consent was obtained. Can students be Principle Investigators?No, only faculty members and preceptors may be Principle Investigators. However, students may work on and submit materials with the Principal Investigator’s permission and guidance.How do I create an account?All applications must be created/submitted via IRBNet.org, an e-protocol system. Create an account by going to IRBNet and clicking the “New User
Registration” link under the login fields in the upper right-hand corner
of the page. When creating your account, make sure you select Kansas
City University of Medicine and Biosciences as your organization. Once
you have created your account, you will receive an activation email.
Please click the link in the email to activate your account. If
experience difficulty when activating your account, please contact
IRBNet support at 877-261-6461.
How do I create an application? To create an application, click on "Create New Project" near the top left-hand corner. Provide the basic project information, upload documentation and share the project with your team members. To submit your application, click on "Submit this Package" and select one or more boards for review.
What additional materials do I need to submit?Elements of a Research ProtocolIACUC Application Materials (PDF)IBC Application Materials (PDF)IRB Application Materials (PDF)Do I have to sign hard copies?Electronic signatures are accepted for all documents except for:
What happens after I submit my application?A preliminary review begins upon receipt of your application, in which the compliance office confirms your application is complete. During this time, you may be asked to modify your application (see how to submit an amendment). Upon confirmation of a complete application, your review will begin. How long is the review?The length of time for review depends on several factors, the largest being when the compliance office plans to convene in relation to when you submit your application. The minimum about of time for review is typically one month for this reason. How do I know my application is approved?Once the committee has rendered a decision, you will receive an automatic e-mail notification. All notifications will be sent to your registered e-mail address. You will be notified via email when a decision is reached and a letter is uploaded to IRBNet org. How long does approval last?IRB and IBC approval cannot exceed one year. IACUC approval cannot exceed three years.How do I renew a study?To renew an application, create a new package from the original project and submit.
When should I renew a study?You have 30 days from your study’s expiration to submit a renewal application. After which, you must submit a new protocol.What happens if my study expires before I receive annual renewal approval?All research activity must cease immediately upon expiration of approval, unless it could jeopardize animal welfare. To recommence research, you must receive an approval letter from the IRB. When should I submit an amendment?Submit an amendment whenever there is a change to the original application materials. How do I submit an amendment?If revisions are needed before your submission is reviewed, your coordinator may unlock the package for you to revise. Unlocked projects can easily be managed from the My Projects page. While the package is unlocked, you may add new documents or revise existing ones as needed.
To revise or submit a previously submitted document for review, refer to the "Documents from Previous Packages" section at the bottom of the Designer page.How do I report an adverse or unanticipated event or suspected non-compliance?Within 48 hours, complete an adverse event form, found on IRBNet.org, and contact your Principal Investigator, if other than you, and the ORSP at 816-654-7605 or firstname.lastname@example.org.
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