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Free CME for KCUMB-COM alumni
KCUMB's Science Friday Talks features lectures and presentations from a broad spectrum of national and international speakers on topics that are relevant to the diverse University community.
Presentations are from 12:30 to 1:30 p.m. in Classroom B of the Annex on KCUMB campus, unless otherwise noted. Lectures are open to KCUMB students, faculty, staff and alumni.
For questions about this event, please contact Dana Buchanan at email@example.com.
Molecular mechanism of synapse organization and its degradation in aging and disease - For the motor function, synaptic connections between spinal cord motor neurons and skeletal muscles are essential. However, in the elderly and amyotrophic lateral sclerosis (ALS) patients, progressive denervation of neuromuscular junctions (NMJs) decreases neuromuscular function, decreases quality of life from frailty, and increases the risk of falling and fractures. Importantly, there are knowledge gaps about the molecular mechanisms that underlie NMJ denervation in aging and ALS. In this seminar, Dr. Nishimune will discuss molecular mechanisms that organize the neurotransmitter release sites at NMJs. Furthermore, Dr. Nishimune will show how these molecular mechanisms are perturbed in aging and ALS, as well as discuss the effort to ameliorate NMJ denervation in aging and ALS using exercise training and stem cells.
Presenter: Dr. Hiroshi Nishimune, Associate Professor - Anatomy and Cell Biology, KU Medical Center Date: March 20, 2015 Time: 12:30 - 1:30 p.m. Location: Classroom B
1750 Independence AvenueKansas City, Mo. 64106-14531-800-234-4847 | 816-654-7000